Are classically singular spacetimes quantum mechanically singular as well?

Are the classical singularities of general relativistic spacetimes, normally defined by the incompleteness of classical particle paths, still singular if quantum mechanical particles are used instead? This is the question we will attempt to answer for particles obeying the quantum mechanical wave equations for scalar, null vector and spinor particles. The analysis will be restricted to certain static general relativistic spacetimes that classically contain the mildest true classical singularities, quasiregular singularities.Comment: 3 pages, no figures, submitted to the Proceedings of the Tenth Marcel Grossmann Meeting on General Relativity, Rio de Janeiro, July 20-26, 200

The energies and residues of the nucleon resonances N(1535) and N(1650)

We extract pole positions for the N(1535) and N(1650) resonances using two different models. The positions are determined from fits to different subsets of the existing $\pi N\to\pi N$, $\pi N\to\eta N$ and $\gamma p\to\eta p$ data and found to be 1515(10)--i85(15)MeV and 1660(10)--i65(10)MeV, when the data is described in terms of two poles. Sensitivity to the choice of fitted data is explored. The corresponding $\pi \pi$ and $\eta \eta$ residues of these poles are also extracted.Comment: 9 page

Substantial regional variation in substitution rates in the human genome: importance of GC content, gene density and telomere-specific effects

This study presents the first global, 1 Mbp level analysis of patterns of nucleotide substitutions along the human lineage. The study is based on the analysis of a large amount of repetitive elements deposited into the human genome since the mammalian radiation, yielding a number of results that would have been difficult to obtain using the more conventional comparative method of analysis. This analysis revealed substantial and consistent variability of rates of substitution, with the variability ranging up to 2-fold among different regions. The rates of substitutions of C or G nucleotides with A or T nucleotides vary much more sharply than the reverse rates suggesting that much of that variation is due to differences in mutation rates rather than in the probabilities of fixation of C/G vs. A/T nucleotides across the genome. For all types of substitution we observe substantially more hotspots than coldspots, with hotspots showing substantial clustering over tens of Mbp's. Our analysis revealed that GC-content of surrounding sequences is the best predictor of the rates of substitution. The pattern of substitution appears very different near telomeres compared to the rest of the genome and cannot be explained by the genome-wide correlations of the substitution rates with GC content or exon density. The telomere pattern of substitution is consistent with natural selection or biased gene conversion acting to increase the GC-content of the sequences that are within 10-15 Mbp away from the telomere.Comment: 35 pages, 6 figure

Distinct changes of genomic biases in nucleotide substitution at the time of mammalian radiation

Differences in the regional substitution patterns in the human genome created patterns of large-scale variation of base composition known as genomic isochores. To gain insight into the origin of the genomic isochores we develop a maximum likelihood approach to determine the history of substitution patterns in the human genome. This approach utilizes the vast amount of repetitive sequence deposited in the human genome over the past ~250 MYR. Using this approach we estimate the frequencies of seven types of substitutions: the four transversions, two transitions, and the methyl-assisted transition of cytosine in CpG. Comparing substitutional patterns in repetitive elements of various ages, we reconstruct the history of the base-substitutional process in the different isochores for the past 250 Myr. At around 90 Myr ago (around the time of the mammalian radiation), we find an abrupt 4- to 8-fold increase of the cytosine transition rate in CpG pairs compared to that of the reptilian ancestor. Further analysis of nucleotide substitutions in regions with different GC-content reveals concurrent changes in the substitutional patterns. While the substitutional pattern was dependent on the regional GC-content in such ways that it preserved the regional GC-content before the mammalian radiation, it lost this dependence afterwards. The substitutional pattern changed from an isochore-preserving to an isochore-degrading one. We conclude that isochores have been established before the radiation of the eutherian mammals and have been subject to the process of homogenization since then

On an acoustic field generated by subsonic jet at low Reynolds numbers

An acoustic field generated by subsonic jets at low Reynolds numbers was investigated. This work is motivated by the need to increase the fundamental understanding of the jet noise generation mechanism which is essential to the development of further advanced techniques of noise suppression. The scope of this study consists of two major investigation. One is a study of large scale coherent structure in the jet turbulence, and the other is a study of the Reynolds number dependence of jet noise. With this in mind, extensive flow and acoustic measurements in low Reynolds number turbulent jets (8,930 less than or equal to M less than or equal to 220,000) were undertaken using miniature nozzles of the same configuration but different diameters at various exist Mach numbers (0.2 less than or equal to M less than or equal to 0.9)